Despite poorer baseline findings with comparable risk factors, mortality was 0% in the HBO group. The positive influence of HBO on the treatment of Fournier's gangrene can be estimated only from the available data. Mortality was 0% in group B and 4.4% in the group A. As análises estatísticas foram realizadas utilizando o programa GraphPad Prism 5 e expressos em média ± EPM (P <0,05). Initial antibiosis was test validated in 80% of the patients in group A and 76.5% of the patients in group B. Para a avaliação da expressão de células microgliais (Iba-1) e de neurogênese (doblecortina - DCX), os encéfalos foram removidos pós-perfusão intracardíaca, 72 h pós-SE. The wound debridement frequency and hospitalization stay were significantly greater in group B (13 vs. The mean ICU stay was 9 and 32 days for patients in groups A and B respectively. Treatment in the intensive care unit (ICU) was therefore indicated in 69% of the patients in group A and 100% of the patients in group B. Sepsis criteria were fulfilled in 77.8 and 100% of the patients in groups A and B respectively. The laboratory parameters C-reactive protein and urea were significantly higher in group B (group B: 301.7 vs.
GRAPHPAD PRISM 6 GUIA DE USO SOFTWARE
Este software tiene la capacidad de dibujar una variedad de gráficos en 3D y también se utiliza para resolver problemas estadísticos. The statistical analysis was performed with GraphPad Prism 7® (GraphPad Software, Inc., La Jolla, USA).ĭemographic data showed no significant differences. GraphPad Prism es el nombre de uno de los productos de software estadístico publicados por una empresa privada llamada GraphPad. The analysis included sex, age, comorbidities, clinical symptoms, laboratory and microbiological data, debridement frequency, wound dressing, antibiotic use, outcome and prognosis. For comparison, 2 groups were distinguished: patients without HBO therapy (group A, n = 45) and patients with HBO therapy (group B, n = 17).
In the present multicenter, retrospective observational study, we evaluated the data of approximately 62 patients diagnosed with Fournier's gangrene between 20. The aim of this study was to investigate the influence of HBO therapy on the outcome and prognosis of Fournier's gangrene. Hyperbaric oxygenation (HBO), in addition to anti-infective and surgical therapy, seems to be a key treatment point for Fournier's gangrene.